H3K9 trimethylation precedes DNA methylation during sheep oogenesis: HDAC1, SUV39H1, G9a, HP1, and Dnmts are involved in these epigenetic events.

@article{Russo2013H3K9TP,
  title={H3K9 trimethylation precedes DNA methylation during sheep oogenesis: HDAC1, SUV39H1, G9a, HP1, and Dnmts are involved in these epigenetic events.},
  author={Valentina Russo and Nicola Bernab{\`o} and Oriana Di Giacinto and Alessandra Martelli and Annunziata Mauro and Paolo Berardinelli and Valentina Curini and Delia Nardinocchi and Mauro Mattioli and Barbara Barboni},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2013},
  volume={61 1},
  pages={75-89}
}
The oocyte, to become a fully mature gamete, has to acquire a correct pattern of DNA methylation on its genome; this epigenetic event represents the major point of the molecular mechanisms that occur during postnatal oogenesis. It is known that an intimate link exists between DNA methylation and histone posttranslational modifications, such as… CONTINUE READING