H2O2 induces DNA repair in mononuclear cells: evidence for association with cytosolic Ca2+ fluxes.

@article{Korzets1999H2O2ID,
  title={H2O2 induces DNA repair in mononuclear cells: evidence for association with cytosolic Ca2+ fluxes.},
  author={Asher Korzets and Avry Chagnac and T Weinstein and Yaacov Ori and Tsipora Malachi and Uzi Gafter},
  journal={The Journal of laboratory and clinical medicine},
  year={1999},
  volume={133 4},
  pages={362-9}
}
Cellular DNA repair systems are induced whenever DNA is damaged. Reactive oxygen species (ROS) are generated, in vivo, in the tissues as a result of regular cellular metabolism or after exposure to oxidizing agents, such as ultraviolet (UV) irradiation. It has been suggested that ROS mediate DNA damage. The objectives of the study were as follows: (1) to investigate whether hydrogen peroxide (H2O2), the commonly occurring cellular ROS, induces DNA repair as a response to the damage it probably… CONTINUE READING
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