H2O2, a Necessary Evil for Cell Signaling

@article{Rhee2006H2O2AN,
  title={H2O2, a Necessary Evil for Cell Signaling},
  author={S. Rhee},
  journal={Science},
  year={2006},
  volume={312},
  pages={1882 - 1883}
}
  • S. Rhee
  • Published 2006
  • Biology
  • Science
  • Once considered lethal to cells, reactive oxygen species are now known to be involved in redox signaling pathways that may contribute to normal cell function as well as disease progression. 
    1,537 Citations
    Peroxiredoxin-2 links Cdk5 to neurodegeneration
    • 16
    Chemokine-dependent T cell migration requires aquaporin-3–mediated hydrogen peroxide uptake
    • 100
    • PDF
    Control of the pericentrosomal H2O2 level by peroxiredoxin I is critical for mitotic progression
    • 51
    • PDF
    SNAP-shots of hydrogen peroxide in cells.
    • 3
    Iron uptake controls the generation of Leishmania infective forms through regulation of ROS levels
    • 74
    • PDF
    Role of sestrin2 in peroxide signaling in macrophages
    • 67
    S-nitrosylation TRiPs a calcium switch
    • 15

    References

    SHOWING 1-8 OF 8 REFERENCES
    Redox Redux: Revisiting PTPs and the Control of Cell Signaling
    • 643
    NOX enzymes and the biology of reactive oxygen
    • J. Lambeth
    • Biology, Medicine
    • Nature Reviews Immunology
    • 2004
    • 2,588
    Regulation of Peroxiredoxin I Activity by Cdc2-mediated Phosphorylation*
    • 222
    • PDF
    Nox2 and Rac1 Regulate H2O2-Dependent Recruitment of TRAF6 to Endosomal Interleukin-1 Receptor Complexes
    • 214
    • PDF
    Subcellular targeting of oxidants during endothelial cell migration
    • 166
    • PDF