H1t/GC-box and H1t/TE1 element are essential for promoter activity of the testis-specific histone H1t gene.


The testis-specific linker histone H1t gene is transcribed exclusively in mid to late pachytene primary spermatocytes. Tissue-specific expression of the gene is mediated primarily through elements located within the proximal promoter. Previous work in transgenic animals identified a unique 40-base pair promoter element designated H1t/TE that is essential… (More)


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