H1-nucleosome interactions and their functional implications.


Linker histones are three domain proteins and consist of a structured (globular) domain, flanked by two likely non-structured NH2- and COOH-termini. The binding of the linker histones to the nucleosome was characterized by different methods in solution. Apparently, the globular domain interacts with the linker DNA and the nucleosome dyad, while the binding… (More)
DOI: 10.1016/j.bbagrm.2015.10.012