H-ras oncogene point mutations in arthritic synovium.


OBJECTIVE To examine mutational activation of ras proto-oncogenes in synovial tissue from patients with rheumatoid arthritis (RA) compared with synovial specimens from patients with osteoarthritis (OA) or other arthropathies. Synovial samples from cadavers, without any signs of joint disease, were used as control material. METHODS Using a combination of… (More)


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@article{Roivainen1997HrasOP, title={H-ras oncogene point mutations in arthritic synovium.}, author={Anne Roivainen and Jari Jalava and Laura Piril{\"a} and Tuomas Yli-Jama and Hannu Tiusanen and Paavo Toivanen}, journal={Arthritis and rheumatism}, year={1997}, volume={40 9}, pages={1636-43} }