H-ras Dependent Estrogenic Effects of Epidermal Growth Factor in the Estrogen-Independent Breast Cancer Cell Line MDA-MB-231

Abstract

A crosstalk between cellular estrogen response and receptor tyrosine kinase signaling has been shown in a variety of estrogen receptor (ER)-positive cell lines. We intended to examine the presence of estrogenic growth factor effects in an ER α-negative breast cancer cell line. By means of reporter gene assays, we investigated the activation of estrogen… (More)
DOI: 10.1023/A:1024502107690

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