H magnetic resonance spectroscopy in the investigation of intractable epilepsy

  title={H magnetic resonance spectroscopy in the investigation of intractable epilepsy},
  author={D. Gadian and A. Connelly and J. S. Duncan and J. Cross and F. J. Kirkham and C. L. Johnson and F. Vargha-Khadem and B. G. R. Nevile and G. D. Jackson},
  journal={Acta Neurologica Scandinavica},
  • D. Gadian, A. Connelly, +7 authors D. Gadian
  • Published 1994
  • Chemistry, Medicine
  • Acta Neurologica Scandinavica
  • We have been using proton magnetic resonance spectroscopy (1H MRS) in the investigation of adults and children with intractable epilepsy. Spectra were obtained from 2 × 2 times 2 cm cubes in the medial region of the temporal lobe, and were analyzed on the basis of signals from N‐acetylaspartate (NAA), creatine+phosphocreatine (Cr), and choline‐containing compounds (Cho). In comparison with control subjects, the epilepsy patients as a group show significant reductions in the NAA signal and in… CONTINUE READING
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