H-Y as a minor histocompatibility antigen in kidney transplantation: a retrospective cohort study.

@article{Gratwohl2008HYAA,
  title={H-Y as a minor histocompatibility antigen in kidney transplantation: a retrospective cohort study.},
  author={Alois A Gratwohl and Bernd D{\"o}hler and Martin Stern and Gerhard Opelz},
  journal={Lancet},
  year={2008},
  volume={372 9632},
  pages={49-53}
}
BACKGROUND In haematopoietic stem-cell transplantation, male recipients of female grafts have an increased risk of graft-versus-host disease and female recipients have both an increased risk of rejection of male grafts and of specific T-cell and antibody reactivity against H-Y encoded gene products. By contrast, in kidney transplantation, the role of H-Y as a minor histocompatibility antigen has been disputed. We aimed to investigate whether an immunological H-Y effect occurs in kidney… CONTINUE READING

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