H-NOX-mediated nitric oxide sensing modulates symbiotic colonization by Vibrio fischeri.

@article{Wang2010HNOXmediatedNO,
  title={H-NOX-mediated nitric oxide sensing modulates symbiotic colonization by Vibrio fischeri.},
  author={Yanling Wang and Yann S. Dufour and Hans K. Carlson and Timothy J. Donohue and Michael A Marletta and Edward G. Ruby},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2010},
  volume={107 18},
  pages={8375-80}
}
The bioluminescent bacterium Vibrio fischeri initiates a specific, persistent symbiosis in the light organ of the squid Euprymna scolopes. During the early stages of colonization, V. fischeri is exposed to host-derived nitric oxide (NO). Although NO can be both an antimicrobial component of innate immunity and a key signaling molecule in eukaryotes, potential roles in beneficial host-microbe associations have not been described. V. fischeri hnoX encodes a heme NO/oxygen-binding (H-NOX) protein… CONTINUE READING
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