Hürthle cell tumors: using molecular techniques to define a novel classification system.

@article{Belchetz2002HrthleCT,
  title={H{\"u}rthle cell tumors: using molecular techniques to define a novel classification system.},
  author={Greg Belchetz and Carol C Cheung and Jeremy L. Freeman and Irving B. Rosen and I. Witterick and Sylvia L Asa},
  journal={Archives of otolaryngology--head & neck surgery},
  year={2002},
  volume={128 3},
  pages={
          237-40
        }
}
BACKGROUND Since ret/PTC gene rearrangements are specific to papillary thyroid carcinoma (PTC), the diagnosis of Hürthle cell PTC (HCPTC) has recently been expanded to include a subset of Hürthle cell tumors (HCTs) that may lack both papillary architecture and/or classic nuclear features but that harbor a ret/PTC gene rearrangement. We hypothesize that such HCPTCs behave in a fashion analogous to other papillary carcinomas, while Hürthle cell carcinomas (HCCs) behave similarly to follicular… CONTINUE READING
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