Gyrification patterns in monozygotic twin pairs varying in discordance for autism.

@article{Kates2009GyrificationPI,
  title={Gyrification patterns in monozygotic twin pairs varying in discordance for autism.},
  author={Wendy R. Kates and I Ikuta and Courtney P. Burnette},
  journal={Autism research : official journal of the International Society for Autism Research},
  year={2009},
  volume={2 5},
  pages={
          267-78
        }
}
In order to disentangle genetic and environmental contributions to cortical anomalies in children with autism, we investigated cortical folding patterns in a cohort of 14 monozygotic (MZ) twin pairs who displayed a range of phenotypic discordance for autism, and 14 typically developing community controls. Cortical folding was assessed with the gyrification index, which was calculated on high resolution anatomic MR images. We found that the cortical folding patterns across most lobar regions of… CONTINUE READING
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