GyrA interacts with MarR to reduce repression of the marRAB operon in Escherichia coli.

Abstract

Bacterial two-hybrid studies of randomly cloned Escherichia coli DNA identified a physical interaction between GyrA, subunit A of gyrase, and MarR, a repressor of the marRAB operon. GyrA-His immobilized on Ni-nitrilotriacetic acid (NiNTA) resin bound MarR, while MarR alone did not bind. GyrA interfered with MarR binding to marO, as detected by… (More)
DOI: 10.1128/JB.00312-11

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Cite this paper

@article{Domain2010GyrAIW, title={GyrA interacts with MarR to reduce repression of the marRAB operon in Escherichia coli.}, author={Francis Domain and Stuart Levy}, journal={Journal of bacteriology}, year={2010}, volume={193 10}, pages={2674} }