Gynaecomastia without lipodystrophy in HIV-1-seropositive patients on efavirenz: an alternative hypothesis.

@article{Qazi2002GynaecomastiaWL,
  title={Gynaecomastia without lipodystrophy in HIV-1-seropositive patients on efavirenz: an alternative hypothesis.},
  author={Nadeem A Qazi and John F. Morlese and David M King and Rizvana S Ahmad and Brian George Gazzard and Mark R. Nelson},
  journal={AIDS},
  year={2002},
  volume={16 3},
  pages={
          506-7
        }
}
Efavirenz-induced gynecomastia in a prepubertal girl with human immunodeficiency virus infection: a case report
TLDR
Timely recognition of gynecomastia as a side-effect of efavirenz is important in order to intervene while the condition may still be reversible, to sustain adherence to ART and to maintain the sociopsychological health of the child. Expand
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Six patients presenting in the treatment program with varying degrees of gynaecomastia following the use of efavirenz-based highly active antiretroviral therapy, despite adequate immunologic and virologic response are reported. Expand
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The present study presented a series of two cases that developed ultrasound confirmed gynaecomastia following efavirenz containing HAART, and suggested that proper identification and management will promote better drug adherence. Expand
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The incidence of gynaecomastia is increasing in men with HIV on HAART therapy, proper identification and management will promote better drug adherence. Expand
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Patients on HAART are advised to seek early advice upon noticing gynaecomastia and management option must be discussed with patients, and surgeons are required to be familiar with the various surgical techniques necessary to treat gynaEComastsia. Expand
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TLDR
The use of EFV and increased age were associated with breast abnormalities in this population of adolescents receiving antiretroviral therapy and further research is needed to better understand the implications of this potential side effect. Expand
Gynecomastia in HIV-positive adult men receiving efavirenz-based antiretroviral therapy at Newlands clinic, Harare, Zimbabwe
TLDR
The incidence of gynecomastia among patients taking efavirenz-based ART was low with most cases developing early on during treatment and most cases resolved completely after withdrawing efvirenz. Expand
HIV-infected adolescents on anti-retroviral therapy: a retrospective descriptive cohort study of breast abnormalities documented during routine care
A research report submitted in submissible format to the Faculty of Health Sciences, University of Witwatersrand, Johannesburg, in partial fulfillment of the requirements for the degree of MSc inExpand
Who Gets Severe Gynecomastia Among HIV-infected Children in the United Kingdom and Ireland?
TLDR
Five HIV-infected children in the UK/Ireland’s national cohort had gynecomastia, of which five were nonreversible, despite changing antiretroviral therapy, and required breast reduction surgery. Expand
Cases of antiretroviral-associated gynaecomastia reported to the National HIV & Tuberculosis Health Care Worker Hotline in South Africa
TLDR
Gynaecomastia was a frequently reported ADR in the setting, occurring with prolonged efavirenz exposure, and most clinicians elected to switch patients off efvirenz, and gynaecamastia improved in the majority. Expand
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