Gymnemic Acids Inhibit Hyphal Growth and Virulence in Candida albicans

@inproceedings{Vediyappan2013GymnemicAI,
  title={Gymnemic Acids Inhibit Hyphal Growth and Virulence in Candida albicans},
  author={Govindsamy Vediyappan and Vincent Dumontet and Franck P{\'e}lissier and Christophe d’Enfert},
  booktitle={PloS one},
  year={2013}
}
Candida albicans is an opportunistic and polymorphic fungal pathogen that causes mucosal, disseminated and invasive infections in humans. Transition from the yeast form to the hyphal form is one of the key virulence factors in C. albicans contributing to macrophage evasion, tissue invasion and biofilm formation. Nontoxic small molecules that inhibit C. albicans yeast-to-hypha conversion and hyphal growth could represent a valuable source for understanding pathogenic fungal morphogenesis… CONTINUE READING
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