Gymnema sylvestre: A Memoir

@article{Kanetkar2007GymnemaSA,
  title={Gymnema sylvestre: A Memoir},
  author={Parijat Kanetkar and Rekha S Singhal and Madhusudan Kamat},
  journal={Journal of Clinical Biochemistry and Nutrition},
  year={2007},
  volume={41},
  pages={77 - 81}
}
Gymnema sylvestre is regarded as one of the plants with potent anti diabetic properties. This plant is also used for controlling obesity in the form of Gymnema tea. The active compound of the plant is a group of acids termed as gymnemic acids. It has been observed that there could be a possible link between obesity, Gymnemic acids and diabetes. This review will try to put forth an overall idea about the plant as well as present a molecular perspective linking the common medicine to the most… Expand
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Gymnema sylvestre is regarded as one of the plant with potent property.Leaves of this plant is used by peoples of Vidisha district for treatment of diabetes.The active compound of this plant is aExpand
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TLDR
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Gymnemagenin-producing Endophytic Fungus Isolated from a Medicinal Plant Gymnema sylvestre R.Br
TLDR
An endophytic fungal strain from the leaves of G. sylvestre which produces gymnemagenin in the medium was isolated and the fungus was identified as Penicillium oxalicum based on morphological and molecular methods. Expand
Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists
TLDR
Deep pharmacological investigation demonstrated that gymnestrogenin, reducing the expression of SREBP1c and ABCA1 in vitro, is able to decrease lipid accumulation in HepG2 cells, substantiate the use of G. sylvestre extract in LXR mediated dislypidemic diseases. Expand
ISOLATION AND CHARACTERIZATION OF GYMNEMIC ACID FROM GYMNEMA SYLVESTRE R.BR. IN CONTROL OF DIABETES
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C-4 Gem-Dimethylated Oleanes of Gymnema sylvestre and Their Pharmacological Activities
TLDR
A literature survey revealed that some other notable pharmacological activities of the plant such as anti-obesity, hypolipidemic, antimicrobial, free radical scavenging and anti-inflammatory properties have been proven too. Expand
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References

SHOWING 1-10 OF 29 REFERENCES
Constuents from Gymnema sylvestre leaves. V. Isolation and preliminary characterization of the gymnemic acids.
The objectives of this investigation were to isolate and characterize the constituents of gymnemic acid, the antisweet principle of Gymnema sylvestre leaves, and to make them available for furtherExpand
Antisweet Natural Products. V. Structures of Gymnemic Acids VIII-XII from Gymnema sylvestre R. BR.
Five oleanane-type triterpenoid saponins, gymnemic acids VIII-XII as antisweet principles were isolated from the leaves of Gymnema sylvestre (Asclepiadaceae). Their structures were established on theExpand
Structure studies of new antisweet constituents from Gymnema sylvestre
Abstract Gymnemic acid I , II , III and IV have been isolated from hot water extract of leaves of Gymnema sylvestre R. Br. as antisweet principles. The whole structures were determined by chemicalExpand
Constituents from Gymnema sylvestre leaves.
Nonacosane, hentriacontane, and tritriacontane were isolated by vapor phase chromatography from a hydrocarbon fraction of Gymnema sylvestre leaves. The cyclic alcohol, conduritol A, rather than theExpand
Studies on taste modifiers. II. Purification and structure determination of gymnemic acids, antisweet active principle from Gymnema sylvestre leaves
Abstract Two major active components of gymnemic acids were isolated in pure state. Their chemical structures were established as D-glucuronide of 3β,16β,21β,22α,23,28-hexahydroxyolean-12-ene whichExpand
Constituents from Gymnema sylvestre leaves. 8. Isolation, chemistry, and derivatives of gymnemagenin and gymnestrogenin.
Isolation of crystalline gymnemagenin and gymnestrogenin directly from the leaves of Gymnema sylvestre, together with preparation of various derivatives of the two aglycones, is described.
Hypoglycaemic activity of an indigenous drug (Gymnema sylvestre, 'Gurmar') in normal and diabetic persons.
TLDR
Recently, Gunnar has been shown to decrease blood glucose levels of normal fasting rabbits and it was considered worthwhile to evaluate hypoglycaemic activity of the drug in normal and diabetic persons. Expand
Antisweet Natural Products. IX. Structures of Gymnemic Acids XV-XVIII from Gymnema sylvestre R. BR. V
Systematic separation of the saponin fraction of the leaves of Gymnema sylvestre has led to the isolation of four new saponins, gymnemic acids XV-XVIII, as antisweet substances. The structures wereExpand
Fecal steroid excretion is increased in rats by oral administration of gymnemic acids contained in Gymnema sylvestre leaves.
TLDR
It is demonstrated for the first time that a high dose of gymnemic acids increases fecal cholesterol and CA-derived bile acid excretion and is correlated with fecal gymnemagenin levels. Expand
In vitro micropropagation of Gymnema sylvestre – A multipurpose medicinal plant
TLDR
The nature of the explant, seedling age, medium type, plant growth regulators, complex extracts and antioxidants markedly influenced in vitro propagation of Gymnema sylvestre and the plantlets were hardened and successfully established in natural soil. Expand
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