Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease.

  title={Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease.},
  author={P. Hegyi and J. Mal{\'e}th and J. Walters and A. F. Hofmann and S. Keely},
  journal={Physiological reviews},
  volume={98 4},
  • P. Hegyi, J. Maléth, +2 authors S. Keely
  • Published 2018
  • Physics, Medicine
  • Physiological reviews
  • Epithelial cells line the entire surface of the gastrointestinal tract and its accessory organs where they primarily function in transporting digestive enzymes, nutrients, electrolytes, and fluid to and from the luminal contents. At the same time, epithelial cells are responsible for forming a physical and biochemical barrier that prevents the entry into the body of harmful agents, such as bacteria and their toxins. Dysregulation of epithelial transport and barrier function is associated with… CONTINUE READING
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