Gut microbiota diversity predicts immune status in HIV-1 infection.

  title={Gut microbiota diversity predicts immune status in HIV-1 infection.},
  author={Piotr Nowak and Marius Troseid and Ekatarina Avershina and Babilonia Barqasho and Ujjwal Neogi and Kristian Holm and Johannes R Hov and Kajsa Noyan and Jan Vesterbacka and Jenny Sv{\"a}rd and Knut Rudi and Anders S{\"o}nnerborg},
  volume={29 18},
OBJECTIVE HIV-1 infection is characterized by altered intestinal barrier, gut microbiota dysbiosis, and systemic inflammation. We hypothesized that changes of the gut microbiota predict immune dysfunction and HIV-1 progression, and that antiretroviral therapy (ART) partially restores the microbiota composition. DESIGN An observational study including 28 viremic patients, three elite controllers, and nine uninfected controls. Blood and stool samples were collected at baseline and for 19… CONTINUE READING


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