Gut microbiota-derived lipopolysaccharide uptake and trafficking to adipose tissue: implications for inflammation and obesity.

@article{Hersoug2016GutML,
  title={Gut microbiota-derived lipopolysaccharide uptake and trafficking to adipose tissue: implications for inflammation and obesity.},
  author={L-G Hersoug and Peter M\oller and Steffen Loft},
  journal={Obesity reviews : an official journal of the International Association for the Study of Obesity},
  year={2016},
  volume={17 4},
  pages={297-312}
}
The composition of the gut microbiota and excessive ingestion of high-fat diets (HFD) are considered to be important factors for development of obesity. In this review we describe a coherent mechanism of action for the development of obesity, which involves the composition of gut microbiota, HFD, low-grade inflammation, expression of fat translocase and scavenger receptor CD36, and the scavenger receptor class B type 1 (SR-BI). SR-BI binds to both lipids and lipopolysaccharide (LPS) from Gram… CONTINUE READING
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