Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

@article{Desbonnet2015GutMD,
  title={Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour},
  author={L Desbonnet and Gerard Clarke and Alexander Traplin and Orla O’Sullivan and John F Cryan},
  journal={Brain, Behavior, and Immunity},
  year={2015},
  volume={48},
  pages={165-173}
}
BACKGROUND There is growing appreciation for the importance of bacteria in shaping brain development and behaviour. Adolescence and early adulthood are crucial developmental periods during which exposure to harmful environmental factors can have a permanent impact on brain function. Such environmental factors include perturbations of the gut bacteria that may affect gut-brain communication, altering the trajectory of brain development, and increasing vulnerability to psychiatric disorders. Here… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 89 extracted citations

Gut Microbiota and the Neuroendocrine System

Neurotherapeutics • 2017
View 7 Excerpts
Highly Influenced

The microbiome-gut-brain axis: implications for schizophrenia and antipsychotic induced weight gain

European Archives of Psychiatry and Clinical Neuroscience • 2017
View 3 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

L Desbonnet
Brain Behav. Immun • 2015

Altered brain-gut axis in autism: comorbidity or causative mechanisms?

BioEssays : news and reviews in molecular, cellular and developmental biology • 2014
View 2 Excerpts

Common polymorphism in the oxytocin receptor gene (OXTR) is associated with human social recognition skills.

Proceedings of the National Academy of Sciences of the United States of America • 2014
View 1 Excerpt

Correlation between the human fecal microbiota and depression.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society • 2014
View 2 Excerpts

Similar Papers

Loading similar papers…