Gut microbiota: Adding weight to the microbiota's role in obesity—exposure to antibiotics early in life can lead to increased adiposity

@article{Ray2012GutMA,
  title={Gut microbiota: Adding weight to the microbiota's role in obesity—exposure to antibiotics early in life can lead to increased adiposity},
  author={K. Ray},
  journal={Nature Reviews Endocrinology},
  year={2012},
  volume={8},
  pages={623-623}
}
  • K. Ray
  • Published 2012
  • Medicine
  • Nature Reviews Endocrinology
Gut microbiota: Adding weight to the microbiota's role in obesity—exposure to antibiotics early in life can lead to increased adiposity 
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12 Citations
Results Citations
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12 Citations

Citation Type

Citation Type

The role of Gut Microbiota in the development of obesity and Diabetes
TLDR
The role of key metabolites mainly the short chain fatty acids that are produced by gut microbiota and how they impact key metabolic pathways such as insulin signalling, incretin production as well as inflammation are looked at. Expand
Gut microbiome and its role in obesity and insulin resistance
TLDR
While the field of gut microbiome and its role in obesity is early in its stage of development, it holds a promising future in providing us with novel therapeutic targets that may restore the gut microbiome to a healthy state and help in the prevention and treatment of obesity. Expand
Related actions of probiotics and antibiotics on gut microbiota and weight modification.
TLDR
The effects of probiotics and antibiotics on the gut microbiota of human beings and animals are presented and their potential therapeutic use as interventions for weight gain and loss in human beings are discussed. Expand
Involvement of the Gut Microbiota and Barrier Function in Glucocorticoid‐Induced Osteoporosis
  • J. Schepper, F. Collins, +8 authors L. McCabe
  • Biology, Medicine
  • Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • 2019
TLDR
The gut is identified as a novel therapeutic target for preventing glucocorticoid‐induced osteoporosis (GIO) and it is identified that bone‐specific Wnt10b overexpression prevented GIO. Expand
Comparative genomics analysis of Lactobacillus species associated with weight gain or weight protection
TLDR
The results of this study revealed that weight protection-associated Lactobacillus spp. Expand
Alterations of the Treatment-Naive Gut Microbiome in Newly Diagnosed Hepatitis C Virus Infection.
TLDR
The findings reveal the alteration of gut microbiota in treatment naive HCV patients and suggest that gut microbiota may hold diagnostic promise in HCV infection. Expand
Effects of Low-Dose Antibiotics on Gut Immunity and Antibiotic Resistomes in Weaned Piglets
TLDR
Findings reveal considerable changes in intestinal immunity-related genes, but minimal effects on gut antibiotic resistomes (ARGs and MGEs) in weaned piglets after 4 weeks LDA exposure, a foundation for evaluating the longer-term cumulative effects of LDA use. Expand
Antibiotic Use and Childhood Body Mass Index Trajectory
TLDR
Evidence is found of reversible, persistent and progressive effects of antibiotic use on BMI trajectories, with different effects by age, among mainly healthy children, suggesting that antibiotic use may influence weight gain throughout childhood and not just during the earliest years as has been the primary focus of most prior studies. Expand
Cesarean delivery and risk of childhood obesity.
TLDR
The hypothesis that an increasing rate of cesarean delivery contributes to obesity in childhood is not supported, and the results do not support the hypothesis that the number of children given birth by c Cesarean may increase the risk of obesity in early childhood. Expand
FOR TREATING OBESITY AND RELATED DSORDERS BY CHARACTERIZING AND RESTORING MAMMALIAN BACTERIAL
  • 2017
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References

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Antibiotics in early life alter the murine colonic microbiome and adiposity
TLDR
A model of adiposity is generated by giving subtherapeutic antibiotic therapy to young mice and changes in the composition and capabilities of the gut microbiome are evaluated, demonstrating the alteration of early-life murine metabolic homeostasis through antibiotic manipulation. Expand
Infant antibiotic exposures and early-life body mass
TLDR
Exposure to antibiotics during the first 6 months of life is associated with consistent increases in body mass from 10 to 38 months, and further studies are needed to isolate effects and define life-course implications for body mass and cardiovascular risks. Expand