Gut microbiome predictors of treatment response and recurrence in primary Clostridium difficile infection.

@article{Khanna2016GutMP,
  title={Gut microbiome predictors of treatment response and recurrence in primary Clostridium difficile infection.},
  author={Sahil Khanna and Emmanuel Montassier and Bradley A Schmidt and Robin Patel and Daniel Knights and D S Pardi and Purna C. Kashyap},
  journal={Alimentary pharmacology & therapeutics},
  year={2016},
  volume={44 7},
  pages={715-727}
}
BACKGROUND Clostridium difficile infection (CDI) may not respond to initial therapy and frequently recurs, but predictors of response and recurrence are inconsistent. The impact of specific alterations in the gut microbiota determining treatment response and recurrence in patients with CDI is unknown. AIM To assess microbial signatures as predictors of treatment response and recurrence in CDI. METHODS Pre-treatment stool samples and clinical metadata including outcomes were collected… CONTINUE READING
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