Gut-liver axis, nutrition, and non-alcoholic fatty liver disease.

  title={Gut-liver axis, nutrition, and non-alcoholic fatty liver disease.},
  author={Irina A Kirpich and Luis S. Marsano and C J Mcclain},
  journal={Clinical biochemistry},
  volume={48 13-14},
Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of diseases involving hepatic fat accumulation, inflammation with the potential progression to fibrosis and cirrhosis over time. NAFLD is often associated with obesity, insulin resistance, and diabetes. The interactions between the liver and the gut, the so-called "gut-liver axis", play a critical role in NAFLD onset and progression. Compelling evidence links the gut microbiome, intestinal barrier integrity, and NAFLD. The dietary… CONTINUE READING
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