Gut inflammation: current update on pathophysiology, molecular mechanism and pharmacological treatment modalities.

@article{Gyires2014GutIC,
  title={Gut inflammation: current update on pathophysiology, molecular mechanism and pharmacological treatment modalities.},
  author={Kl{\'a}ra Gyires and {\'E}va Vikt{\'o}ria T{\'o}th and S{\'a}ndor Zolt{\'a}n Z{\'a}dori},
  journal={Current pharmaceutical design},
  year={2014},
  volume={20 7},
  pages={
          1063-81
        }
}
Inflammatory bowel disease (IBD) is a chronic and relapsing inflammatory condition of the gastrointestinal tract. The two main forms of IBD are Crohn's disease and ulcerative colitis. According to the recent concept the disease is caused by a combination of factors, including genetics, immune dysregulation, barrier dysfunction and the change in microbial flora. Environmental factors, such as changes in diet, antibiotic use, smoking or improved domestic hygiene (e.g. eradication of intestinal… CONTINUE READING