Gut hormones and the regulation of energy homeostasis

  title={Gut hormones and the regulation of energy homeostasis},
  author={K. Murphy and S. Bloom},
  • K. Murphy, S. Bloom
  • Published 2006
  • Biology, Medicine
  • Nature
  • Food intake, energy expenditure and body adiposity are homeostatically regulated. Central and peripheral signals communicate information about the current state of energy balance to key brain regions, including the hypothalamus and brainstem. Hunger and satiety represent coordinated responses to these signals, which include neural and hormonal messages from the gut. In recent years our understanding of how neural and hormonal brain–gut signalling regulates energy homeostasis has advanced… CONTINUE READING
    635 Citations

    Paper Mentions

    AIMS Phase 1. Verify whether the intake of LibramedR is able to induce a better endocrine and metabolic profile. Phase 2. Verify whether treatment with LibramedR for 60… Expand
    Bowels control brain: gut hormones and obesity
    • 3
    Brain regulation of appetite and satiety.
    • R. Ahima, D. Antwi
    • Medicine
    • Endocrinology and metabolism clinics of North America
    • 2008
    • 213
    The role of the gut/brain axis in modulating food intake
    • 122
    • Highly Influenced
    • PDF
    Neuronal regulation of homeostasis by nutrient sensing
    • T. Lam
    • Biology, Medicine
    • Nature Medicine
    • 2010
    • 110
    [Appetite regulation: neuroendocrine basis and clinical approaches].
    • 1
    • Highly Influenced
    Gut–brain cross-talk in appetite regulation
    • 21
    Energy Homeostasis and Obesity: The Therapeutic Role of Anorexigenic and Orexigenic Peptide
    • 1
    Peptides and Food Intake
    • 162
    • PDF


    Ghrelin action in the brain controls adipocyte metabolism.
    • 387
    • PDF
    Central nervous system control of food intake
    • 5,745
    • PDF
    Ghrelin induces adiposity in rodents
    • 3,637
    Effects of obestatin on energy balance and growth hormone secretion in rodents.
    • 266
    • PDF
    Anatomy and regulation of the central melanocortin system
    • R. Cone
    • Biology, Medicine
    • Nature Neuroscience
    • 2005
    • 1,295
    • PDF
    Ghrelin and the short- and long-term regulation of appetite and body weight
    • 547
    Critical role for peptide YY in protein-mediated satiation and body-weight regulation.
    • 527
    • PDF
    Pancreatic polypeptide reduces appetite and food intake in humans.
    • 442
    • PDF