Gut homeostasis in a microbial world: insights from Drosophila melanogaster

  title={Gut homeostasis in a microbial world: insights from Drosophila melanogaster},
  author={N. Buchon and Nichole A. Broderick and B. Lema{\^i}tre},
  journal={Nature Reviews Microbiology},
  • N. Buchon, Nichole A. Broderick, B. Lemaître
  • Published 2013
  • Biology, Medicine
  • Nature Reviews Microbiology
  • Intestinal homeostasis is achieved, in part, by the integration of a complex set of mechanisms that eliminate pathogens and tolerate the indigenous microbiota. Drosophila melanogaster feeds on microorganism-enriched matter and therefore has developed efficient mechanisms to control ingested microorganisms. Regulatory mechanisms ensure an appropriate level of immune reactivity in the gut to accommodate the presence of beneficial and dietary microorganisms, while allowing effective immune… CONTINUE READING
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