Gut-derived signaling molecules and vagal afferents in the control of glucose and energy homeostasis.

@article{Thorens2004GutderivedSM,
  title={Gut-derived signaling molecules and vagal afferents in the control of glucose and energy homeostasis.},
  author={Bernard Thorens and Philip Just Larsen},
  journal={Current opinion in clinical nutrition and metabolic care},
  year={2004},
  volume={7 4},
  pages={471-8}
}
PURPOSE OF REVIEW The control of glucose and energy homeostasis, including feeding behaviour, is tightly regulated by gut-derived peptidic and nonpeptidic endocrine mediators, autonomic nervous signals, as well as nutrients such as glucose. We will review recent findings on the role of the gastrointestinal tract innervation and of portal vein glucose sensors; we will review selected data on the action of gastrointestinally released hormones. RECENT FINDINGS The involvement of mechanosensory… CONTINUE READING

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