Gut barrier dysfunction in food allergy

  title={Gut barrier dysfunction in food allergy},
  author={Martine Heyman},
  journal={European Journal of Gastroenterology \& Hepatology},
  • M. Heyman
  • Published 1 December 2005
  • Medicine, Biology
  • European Journal of Gastroenterology & Hepatology
Intestinal permeability tests used in the diagnosis of allergic diseases in response to oral food challenge have led to the conclusion that constitutive defects of the intestinal barrier are not the primary cause of allergic diseases. However, perturbation of environmental factors (infection, stress), by increasing intestinal permeability and enhancing danger signals, may favour food allergy in susceptible individuals. The mechanisms of enhanced permeability to specific and bystander antigens… 

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