Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates

  title={Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates},
  author={L{\'i}via S. Zaramela and Cameron Martino and Frederico Alisson-Silva and Steven D. Rees and Sandra L Diaz and L{\'e}a Chuzel and Mehul B. Ganatra and Christopher H. Taron and Patrick Secrest and Cristal Zu{\~n}iga and Jianbo Huang and Dionicio Siegel and Geoffrey A Chang and Ajit Varki and Karsten Zengler},
  journal={Nature microbiology},
  pages={2082 - 2089}
Dietary habits have been associated with alterations of the human gut resident microorganisms contributing to obesity, diabetes and cancer1. In Western diets, red meat is a frequently eaten food2, but long-term consumption has been associated with increased risk of disease3,4. Red meat is enriched in N-glycolylneuraminic acid (Neu5Gc) that cannot be synthesized by humans5. However, consumption can cause Neu5Gc incorporation into cell surface glycans6, especially in carcinomas4,7. As a… 

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