Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates

@article{Zaramela2019GutBR,
  title={Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates},
  author={Livia S Zaramela and C. Martino and Frederico Alisson-Silva and S. D. Rees and S. Diaz and L. Chuzel and M. Ganatra and C. Taron and P. Secrest and C. Zu{\~n}iga and Jianbo Huang and D. Siegel and G. Chang and A. Varki and K. Zengler},
  journal={Nature microbiology},
  year={2019},
  volume={4},
  pages={2082 - 2089}
}
Dietary habits have been associated with alterations of the human gut resident microorganisms contributing to obesity, diabetes and cancer1. In Western diets, red meat is a frequently eaten food2, but long-term consumption has been associated with increased risk of disease3,4. Red meat is enriched in N-glycolylneuraminic acid (Neu5Gc) that cannot be synthesized by humans5. However, consumption can cause Neu5Gc incorporation into cell surface glycans6, especially in carcinomas4,7. As a… Expand
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