Gut REG3γ-Associated Lactobacillus Induces Anti-inflammatory Macrophages to Maintain Adipose Tissue Homeostasis

@article{Huang2017GutRL,
  title={Gut REG3$\gamma$-Associated Lactobacillus Induces Anti-inflammatory Macrophages to Maintain Adipose Tissue Homeostasis},
  author={Yugang Huang and Houbao Qi and Zhiqiang Zhang and Enlin Wang and Huan Yun and Hui Yan and Xiaomin Su and Yingquan Liu and Zenzen Tang and Yunhuan Gao and Wencong Shang and Jiang Zhou and Tianze Wang and Y. Che and Y. Zhang and Rongcun Yang},
  journal={Frontiers in Immunology},
  year={2017},
  volume={8}
}
Gut microbiota may not only affect composition of local immune cells but also affect systemic immune cells. However, it is not completely clear how gut microbiota modulate these immune systems. Here, we found that there exist expanded macrophage pools in huREG3γtgIEC mice. REG3γ-associated Lactobacillus, which is homology to Lactobacillus Taiwanese, could enlarge macrophage pools not only in the small intestinal lamina propria but also in the spleen and adipose tissues. STAT3-mediated signal(s… Expand
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References

SHOWING 1-10 OF 52 REFERENCES
Microbiota-Dependent Crosstalk Between Macrophages and ILC3 Promotes Intestinal Homeostasis
Macrophages in intestinal homeostasis and inflammation
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
Stat3 in Resident Macrophages as a Repressor Protein of Inflammatory Response1
Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria.
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5
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