Gut Microbiota Composition Before and After Use of Proton Pump Inhibitors

@inproceedings{Hojo2018GutMC,
  title={Gut Microbiota Composition Before and After Use of Proton Pump Inhibitors},
  author={Mariko Hojo and Takashi Asahara and A H Hori Nagahara and Tsutomu Takeda and Kimikazu Matsumoto and Hiroya Ueyama and Kenshi Matsumoto and Daisuke Asaoka and Takuya Takahashi and Koji Nomoto and Yuichiro Yamashiro and Sumio Watanabe},
  booktitle={Digestive Diseases and Sciences},
  year={2018}
}
BackgroundRecently, problems associated with proton pump inhibitor (PPI) use have begun to surface. PPIs influence the gut microbiota; therefore, PPI use may increase the risk of enteric infections and cause bacterial translocation. In this study, we investigated fecal microbiota composition, fecal organic acid concentrations and pH, and gut bacteria in the blood of the same patients before and after PPI use.MethodsTwenty patients with reflux esophagitis based on endoscopic examination received… CONTINUE READING
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