Gut Microbiota, Nitric Oxide, and Microglia as Prerequisites for Neurodegenerative Disorders.

@article{Tse2017GutMN,
  title={Gut Microbiota, Nitric Oxide, and Microglia as Prerequisites for Neurodegenerative Disorders.},
  author={Joyce K Y Tse},
  journal={ACS chemical neuroscience},
  year={2017},
  volume={8 7},
  pages={1438-1447}
}
Regulating fluctuating endogenous nitric oxide (NO) levels is necessary for proper physiological functions. Aberrant NO pathways are implicated in a number of neurological disorders, including Alzheimer's disease (AD) and Parkinson's disease. The mechanism of NO in oxidative and nitrosative stress with pathological consequences involves reactions with reactive oxygen species (e.g., superoxide) to form the highly reactive peroxynitrite, hydrogen peroxide, hypochloride ions and hydroxyl radical… CONTINUE READING
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