Gut Microbes: From Bugs to Drugs

@article{Shanahan2010GutMF,
  title={Gut Microbes: From Bugs to Drugs},
  author={F Shanahan},
  journal={The American Journal of Gastroenterology},
  year={2010},
  volume={105},
  pages={275-279}
}
A poorly appreciated truism is that the information contained within the mammalian genome is insufficient for full development of several organ systems, notably the gut, immune system, and other sensory organs. The required information is derived from the environment, including the microbial environment. This suggests that the microbiota is a source of regulatory signals, some of which may be suitable for exploitation for therapeutic purposes. Indeed, it could have been deduced from comparative… CONTINUE READING