Gut Feelings About α‐Synuclein in Gastrointestinal Biopsies: Biomarker in the Making?

@inproceedings{Stefanova2016GutF,
  title={
Gut Feelings About α‐Synuclein in Gastrointestinal Biopsies: Biomarker in the Making?},
  author={Nadia Stefanova and Jeffrey H. Kordower and Gregor Karl Wenning and Claudio Ruffmann and L Parkkinen},
  booktitle={Movement disorders : official journal of the Movement Disorder Society},
  year={2016}
}
In recent years, several studies have investigated the potential of immunohistochemical detection of α-synuclein in the gastrointestinal tract to diagnose Parkinson's disease (PD). Although methodological heterogeneity has hindered comparability between studies, it has become increasingly apparent that the high sensitivity and specificity reported in preliminary studies has not been sustained in subsequent large-scale studies. What constitutes pathological α-synuclein in the alimentary canal… CONTINUE READING
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