Gut–brain axis: how the microbiome influences anxiety and depression

@article{Foster2013GutbrainAH,
  title={Gut–brain axis: how the microbiome influences anxiety and depression},
  author={J. Foster and Karen A Neufeld},
  journal={Trends in Neurosciences},
  year={2013},
  volume={36},
  pages={305-312}
}
Within the first few days of life, humans are colonized by commensal intestinal microbiota. Here, we review recent findings showing that microbiota are important in normal healthy brain function. We also discuss the relation between stress and microbiota, and how alterations in microbiota influence stress-related behaviors. New studies show that bacteria, including commensal, probiotic, and pathogenic bacteria, in the gastrointestinal (GI) tract can activate neural pathways and central nervous… Expand
1,169 Citations

Paper Mentions

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Theory and research on the gut-brain-axis emphasize complex interactions between the gut microbiota, immunological and hormonal responses, brain function, brain structure, as well as… Expand
ConditionsAnxiety, Depressive Symptoms, Stress
InterventionDietary Supplement, Other
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References

SHOWING 1-10 OF 99 REFERENCES
Normal gut microbiota modulates brain development and behavior
  • 1,454
  • PDF
Reduced anxiety‐like behavior and central neurochemical change in germ‐free mice
  • 852
Bacterial infection causes stress-induced memory dysfunction in mice
  • 520
  • PDF
Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
  • 1,844
  • PDF
The microbiome is essential for normal gut intrinsic primary afferent neuron excitability in the mouse
  • 186
...
1
2
3
4
5
...