Gut–brain axis: how the microbiome influences anxiety and depression

  title={Gut–brain axis: how the microbiome influences anxiety and depression},
  author={Jane A Foster and Karen-Anne McVey Neufeld},
  journal={Trends in Neurosciences},
Within the first few days of life, humans are colonized by commensal intestinal microbiota. Here, we review recent findings showing that microbiota are important in normal healthy brain function. We also discuss the relation between stress and microbiota, and how alterations in microbiota influence stress-related behaviors. New studies show that bacteria, including commensal, probiotic, and pathogenic bacteria, in the gastrointestinal (GI) tract can activate neural pathways and central nervous… CONTINUE READING
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Publications referenced by this paper.
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The microbiome is essential for normal gut intrinsic primary afferent neuron excitability in the mouse.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society • 2013

The gut microbiota profile is associated with insulin action in humans

M Serino
Acta Diabetol • 2012

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