Guinea pig maximization test of the bark extract from pawpaw, Asimina triloba (Annonaceae)

  title={Guinea pig maximization test of the bark extract from pawpaw, Asimina triloba (Annonaceae)},
  author={Javier Avalos and J. Kent Rupprecht and Jerry McLaughlin and Eloy Rodr{\'i}guez},
  journal={Contact Dermatitis},
Several acetogenins, characteristic of the Annonaceae, have been found to exhibit pesticidal and feeding‐deterrent activities against a variety of pests and are undergoing commercial development as pesticides. The sensitizing potential of one of these plants, pawpaw. Asmina triloba Dunal, was examined in the current study. The potential of Fraction F020 (a pesticidal crude extract of pawpaw stem bark) to sensitize and elicit an allergic contact dermatitis response was determined by using a… 

A novel mechanism for the control of clinical cancer : Inhibition of the production of adenosine triphosphate ( ATP ) with a standardized extract of paw paw ( Asimincz triloba , Annonaceae )

A standardized extract of paw paw reduced tumor markers, reduced tumor sizes, and increased longevities among 94 cancer patients while causing minimal side effects and offers a novel, safe, and effective mechanism for the control of various types of clinical cancer.



Unusual contact allergens from plants in the family Hydrophyllaceae

The dermatitic constituents of the glandular hairs of plants in the family Hydrophyllaceae comprise a class of uncommon natural products called “phacelioids”, which are equivalent to the urushiols of Toxicadendron (Rhus) in their capacity to sensitize humans.

Annonaceous acetogenins: a review.

The Annonaceous acetogenins are a series of apparently polyketide-derived fatty acid derivatives that possess tetrahydrofuran rings and a methylated gamma-lactone (sometimes rearranged to a methyl


Some seven or eight years ago, in late summer, I found in this vicinity several fruits of the common papaw which had fallen to the ground and ripened prematurely and ate a small portion, and experienced an urticaria, beginning with itching and burning in the hair at the back of the head and soon extending over a considerable part of the body.

Inhibition of Respiration at Site I by Asimicin, an Insecticidal Acetogenin of the Pawpaw, Asimina triloba (Annonaceae)

Evidence is found of a site of inhibition between NADH and ubiquinone (site 1) within the electron transport chain within the electrons of Asimina triloba Dunal.