Guillain-Barré syndrome: clinical profile and management

  title={Guillain-Barr{\'e} syndrome: clinical profile and management},
  author={Sreenivasa Rao Sudulagunta and Mahesh Babu Sodalagunta and Mona Sepehrar and Hadi Khorram and Shiva Kumar Bangalore Raja and Shyamala Krishnaswamy Kothandapani and Zahra Noroozpour and Mohammed Aheta Sham and Nagendra K. Prasad and Sony Parethu Sunny and Munawar Dhanish Mohammed and Rekha Gangadharappa and Ranjitha Nidsale Sudarshan},
  journal={GMS German Medical Science},
Introduction: Guillain-Barré syndrome (GBS) is a fulminant polyradiculoneuropathy that is acute, frequently severe and autoimmune in nature. Etiology of GBS is incompletely understood, prognosis is usually good with early detection and prompt treatment. This retrospective study was done to evaluate clinical profile, epidemiological, laboratory, and electrodiagnostic features of patients with GBS and mode of management, complications and prognostic factors. Methods: Data of 1,166 patients… 

Guillain-Barré syndrome: Clinical profile and Consensus to revise Hughes grade 5

Early diagnosis of respiratory failure and prompt intervention improves patient outcome, and a significant association was found between low Medical research sum score (MRC) and respiratory failure.

Outcome of Guillain–Barré Syndrome in Tertiary Care Centers in Thailand

This study suggests that most GBS patients in Thailand are acute inflammatory demyelinating polyradiculoneuropathy (AIDP) subtype and have a good outcome.

Clinical profile of childhood Guillain-Barre Syndrome

The clinical characteristics of Guillain–Barre syndrome in children are not consistent and differ from geographical area and racial diversity.

Clinical spectrum and outcome of guillain-barré syndrome with plasmapheresis

Plasmapheresis should be initiated early in the management of GBS where intravenous immunoglobulins are costly and majority of participants were able to walk without support at the 6-month follow-up.

Mortality Outcome in Patients of Guillian Barre Syndrome. A single Center Study

The independent predictors for the need of mechanical ventilation were history of breathlessness on admission, SBC of equal to or less than 10, upper or lower limb power of less than or equal to 2 (P valve <0.01), and presence of sepsis, need for mechanical ventilation, VAP, S BC of < 10 and lower limb.

Seasonal characteristics and clinical treatment in the Guillaine-Barré syndrome 63 evaluation of the patient series

In this study, axonal form in GBS patients was more frequent in spring and summer seasons, and those who are seen in the spring are better be haved and the treatment is worse in the winter months while thetreatment is better.

Outcomes of patients presenting with Guillain-Barre Syndrome at a tertiary care center in India

Early cranial nerve and respiratory involvement in patients presenting with GBS are associated with poor outcomes warranting immediate critical care involvement, and amongst all the subtypes, axonal had poor clinical outcomes.

Clinical Profile, Electrodiagnostic Variations, Treatment and Outcome in Guillain-Barré Syndrome: Prospective Study of 78 Patients

Plasmapheresis and IVIG both showed similar efficacy in treating GBS, which is more common in male as compare to female and patients who received treatment early in the course of disease had faster recovery.

Guillain Barre Syndrome: Symptoms, Diagnosis and Treatment

Cerebrospinal fluid evaluation and electrophysiological findings are used mainly to diagnose GBS and Plasma exchange and intravenous immunoglobulin play a vital part in the treatment of GBS.

Evaluation of 52 patients with Guillain Barré syndrome between 2015 and 2019 in Kocaeli, Turkey – An epidemiological study

The study revealed both consistent and contradicting findings to the literature that may lead further debate/research on the epidemiology of GBS.



Guillain-Barré syndrome

Both acute mortality and long-term disability in GBS seem to be related to an axonal involvement and a Hughes grade ≥2 at nadir, and after adjustment to US population, the incidence rates for GBS from different countries showed no significant differences.

Guillain-Barré syndrome in Taiwan: a clinical study of 167 patients

Guillain-Barré syndrome in Taiwan showed a peculiar age and seasonal distribution and a high frequency of FS not seen in other series, which suggests AIDP and FS may have similar underlying pathological mechanisms.

Clinical presentation and course of childhood Guillain-Barré syndrome: a prospective multicentre study.

Presenting symptoms, clinical course and paraclinical findings in childhood Guillain-Barré syndrome (GBS) have rarely been investigated prospectively and the results of earlier retrospective investigations are confirmed.

Clinical features, pathogenesis, and treatment of Guillain-Barré syndrome

Guillain-Barré syndrome and SIADH

SIADH is a common and important electrolyte disorder encountered in Guillain-Barré syndrome and has significant association with severity of GBS and is an indicator of poor prognosis.

[Guillain-Barre syndrome in the paediatric age: epidemiological, clinical and therapeutic profile in a hospital in El Salvador].

GBS occurs predominantly in the rainiest season of the year, which is related to an increase in the number of infections in the upper respiratory tract and gastroenteric infections that give rise to a predisposition to present secular outbreaks of the disease.

Guillain-Barrésyndrome in children: a cooperative study in Taiwan

Guillain-Barré syndrome: An update

[Guillain-Barré syndrome].

High-dose of intravenous immunoglobulin (0.4 g/kg daily for 5 days) and PE are equally effective in intermediate and severe forms and the choice between the two treatments depends on their respective contra-indications and local availability.