Guidelines on the use of high-dose intravenous immunoglobulin in dermatology.

@article{Enk2009GuidelinesOT,
  title={Guidelines on the use of high-dose intravenous immunoglobulin in dermatology.},
  author={Alexander H. Enk},
  journal={European journal of dermatology : EJD},
  year={2009},
  volume={19 1},
  pages={
          90-8
        }
}
  • A. Enk
  • Published 2009
  • Medicine
  • European journal of dermatology : EJD
The treatment recommendations presented for the use of IVIg in dermatology highlight the high status of IVIg therapy in numerous defined dermatological autoimmune diseases and in toxic epidermal necrolysis. The high value of IVIg therapy in diseases which are otherwise refractory to treatment is undisputed. A clear case therefore exists for making a treatment recommendation such as described above for the conditions mentioned. Because the mechanism of action of IVIG in vivo is still unclear… 
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Treatment of Toxic Epidermal Necrolysis with the Combination of Infliximab and High-Dose Intravenous Immunoglobulin
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References

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TLDR
This manuscript documents the expert consensus on the use of IVIG in dermatology and reflects current clinical practice and should be a guideline for the practitioner for the use in dermatologic diseases.
Dermatological uses of high-dose intravenous immunoglobulin.
TLDR
High-dose intravenous immunoglobulin (hdIVIg) is increasingly used to treat a range of inflammatory and autoimmune diseases, and liaison between the dermatologist and the immunologist is helpful because it allows the use of both the nursing and the medical expertise of an existing immunotherapy unit.
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TLDR
The current knowledge of the mode of action of intravenous immunoglobulin, its reported therapeutic effects in cutaneous disease, its mode of administration and safety profile, and compares the currently available intravenous vaccine preparations are reviewed.
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TLDR
The experience with a series of patients with Scleromyxedema is described and the use of intravenous immunoglobulin (IVIG) for long-term management is focused on, highlighting the potential therapeutic benefit of IVIG in this condition.
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TLDR
This clinical trial in some of the more refractory cases of juvenile dermatomyositis showed clinical improvement at some point in their treatment with intravenous immunoglobulin, prompted by the reported benefit in a number of childhood illnesses.
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TLDR
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TLDR
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TLDR
It is suggested that in the presence of a steroid and immunosuppressive-resistant autoimmune disease, IVIg is a rational and safe choice.
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