Guidelines for treatment of onychomycosis

  title={Guidelines for treatment of onychomycosis},
  author={D T Roberts and W D Taylor and J. Boyle},
  journal={British Journal of Dermatology},
Summary These guidelines for management of onychomycosis have been prepared for dermatologists on behalf of the British Association of Dermatologists. They present evidence‐based guidance for treatment, with identification of the strength of evidence available at the time of preparation of the guidelines, and a brief overview of epidemiological aspects, diagnosis and investigation. 

Current treatment of onychomycosis.

  • D. Thappa
  • Medicine
    Indian journal of dermatology, venereology and leprology
  • 2007
Therapeutic options for the treatment of onychomycosis range from no therapy, palliative care, mechanical or chemical debridement, topical and systemic antifungal agents to a combination of two or

Treatment of onychomycosis caused by dermatophytes--an opinion proposed by Committee for Standardization of the Japanese Society for Medical Mycology 2007.

Clinical problems concerning this disease are discussed, recommendable treatments for each patient with topical and/or systemic use of antifungal agents are proposed and the necessity of "order-made" therapy for each patients with his/her medical status and wishes taking into account is stressed.

Take a multifaceted approach when treating onychomycosis

Because onychomycosis has a high recurrence rate, preventive measures are recommended even after achieving a cure.

Potential role of tavaborole for the treatment of onychomycosis.

Tavaborole 5.0% nail solution is the first member of a new class of antifungals that has been developed as a new topical nail solution for the treatment of toenail onychomycosis caused by dermatophytes.

Acitretin: Could it be a new therapeutic player in the field of onychomycosis?

The therapeutic use of acitretin is investigated in onychomycosis following the successful treatment of recurrent dermatophytosis with isotretinoin and itraconazole and the complete cure rate with itrachoazole pulse therapy remains unsatisfactory.

Onychomycosis treatment in the United States.

Major trends in the prescription and use of antifungal agents for treatment of onychomycosis in the United States were evaluated using data from the National Ambulatory Medical Care Survey.

Onychomycosis - a review of its presentation and treatment

Data from recently published studies have demonstrated an increased mycological and clinical cure rate using a combination of topical and oral antifungal agents, and this approach may be a cost-effective means of improving outcomes for patients with more resistant nail disease.

Clinical diagnosis of toenail onychomycosis is possible in some patients: cross‐sectional diagnostic study and development of a diagnostic rule

A large number of patients with suspected toenail onychomycosis have had their nails removed or removed with a claw machete, leading to fears that the nails may be infected with bacteria.

Topical and oral combination therapy for toenail onychomycosis: an updated review.

  • I. BristowR. Baran
  • Medicine, Biology
    Journal of the American Podiatric Medical Association
  • 2006
Although effective, oral antifungal therapy is still not completely successful, and additional measures, such as mechanical intervention, may help improve response rates further.

Treatment of Onychomycosis: An Update

Medicated nail lacquers have been developed for the treatment of fungal infections i.e. onychomycosis, which has less toxicity and shorter treatment period than oral antifungal agents.



Factors that may affect the response of onychomycosis to oral antifungal therapy

With the advent of the newer oral antifungals available to treat onychomycosis, the majority of patients respond to therapy. However, there may be subsets of patients who exhibit poor response or

The new oral antifungal agents for onychomycosis of the toenails

  • Aditya K. GuptaN. Shear
  • Medicine, Biology
    Journal of the European Academy of Dermatology and Venereology : JEADV
  • 1999
To review the use of the new oral antifungal agents, itraconazole, terbinafine and fluconazole for the treatment of onychomycosis of the toenails.

Long‐term efficacy of antifungals in toenail onychomycosis: a critical review

A large number of patients treated with antifungal drugs achieve high mycological and clinical cure rates in onychomycosis of the toes, but little is known about the long‐term evolution of the treated patients.


This work has shown that treatment schedules with effective concentrations for 3 months cause drug deposits in nail plates that persist 6 months after the end of the treatment, which is inconsistent with previous trials.

Onychomycosis in elderly chiropody patients

A higher proportion of men than of women in the same age range were infected both by dermatophytes and moulds, and large quantities of several yeast species were grown from thirteen microscopically negative nails.

Topical amorolfine for 15 months combined with 12 weeks of oral terbinafine, a cost‐effective treatment for onychomycosis

  • R. Baran
  • Medicine
    The British journal of dermatology
  • 2001
The efficacy of a combination of oral terbinafine and topical amorolfine in the treatment of severe dermatophyte toenail onychomycosis with matrix area involvement was examined.

Oral treatments for toenail onychomycosis: a systematic review.

There is good evidence that a continuous regimen of terbinafine (250 mg/d) for 3 months is the most effective oral treatment for fungally infected toenails.

The prevalence of onychomycosis in Finland

The prevalence of onychomycosis among ordinary people aged between 6 and 80 years, in different age groups, is found to be much higher than those reported in the earlier studies made elsewhere in Europe.

Tioconazole nail solution—an open study of its efficacy in onychomycosis

The results indicate that cures of onychomycosis are possible after topical therapy, and further methods of using this form of treatment such as combined surgical and topical therapy are discussed.

Prevalence of onychomycosis in patients attending a dermatology clinic in northeastern Ohio for other conditions.

This study investigated 800 individuals aged 6 to 80 years in Finland and yielded a higher onychomycosis prevalence of nail fungal infections than previously investigated, in contrast to the previously mentioned studies.