Guidelines for monitoring patients taking tamoxifen treatment.

  title={Guidelines for monitoring patients taking tamoxifen treatment.},
  author={Patrick Neven and Hilde Vernaeve},
  journal={Drug safety},
  volume={22 1},
Tamoxifen is the most important anti-breast cancer drug in clinical use and has the potential to be used as a chemopreventive breast cancer agent. Using outpatient hysteroscopy and based on 2 case control and 2 cohort follow-up studies in our department, we were able to demonstrate that 50% of women receiving long term tamoxifen experienced some sort of adverse endometrial effects. Although many women retain an atrophic endometrial layer, tamoxifen intake can lead to extensive senile cystic… CONTINUE READING


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