Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.

@article{Hill2005GuidelineFT,
  title={Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.},
  author={Ivor D. Hill and Martha H. Dirks and Gregory S. Liptak and Richard B. Colletti and Alessio Fasano and Stefano Guandalini and Edward J Hoffenberg and K{\'a}roly Horv{\'a}th and Joseph A. Murray and Mitchell Pivor and Ernest G Seidman},
  journal={Journal of pediatric gastroenterology and nutrition},
  year={2005},
  volume={40 1},
  pages={
          1-19
        }
}
Celiac disease is an immune-mediated enteropathy caused by a permanent sensitivity to gluten in genetically susceptible individuals. It occurs in children and adolescents with gastrointestinal symptoms, dermatitis herpetiformis, dental enamel defects, osteoporosis, short stature, delayed puberty and persistent iron deficiency anemia and in asymptomatic individuals with type 1 diabetes, Down syndrome, Turner syndrome, Williams syndrome, selective immunoglobulin (Ig)A deficiency and first degree… Expand

Paper Mentions

Interventional Clinical Trial
This study was designed as a randomized controlled experimental study to examine the effects of peer-interaction group support in adolescents with celiac disease (CD) in the 13-18 age… Expand
ConditionsCeliac Disease in Children
InterventionBehavioral, Other
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Celiac disease (CD) is an autoimmune disorder occurring in genetically susceptible individuals, being characterized by inflammatory injury of the small intestine mucosa after ingestion of wheatExpand
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TLDR
Celiac disease, as diagnosed by positive endomysial antibody tests, has an increased prevalence in children with Downs syndrome in the U.S. as compared with the general population (1/250). Expand
Prevalence and clinical picture of celiac disease in Turner syndrome.
TLDR
The subclinical picture in 60% of the cases, the diagnostic delay, and the incidence of other autoimmune disorders suggest that routine screening of CD in TS is indicated, confirming the high prevalence of celiac disease in a large series of TS patients. Expand
Prevalence and diagnosis of celiac disease in IgA-deficient children.
TLDR
It is suggested that positive IgG-antigliadin antibodies can be used to select IgA-deficient children for jejunal biopsy with a very low probability of missing celiac disease while allowing a drastic reduction in the number of biopsies performed. Expand
Prevalence and clinical features of selective immunoglobulin A deficiency in coeliac disease: an Italian multicentre study. Italian Society of Paediatric Gastroenterology and Hepatology (SIGEP) and "Club del Tenue" Working Groups on Coeliac Disease.
TLDR
Serum IgA should be measured in order to be able to interpret negative results for IgA anti-gliadin antibodies and anti-endomysial antibodies in patients being screened for CD, since some patients with CD and SIgAD may be negative for IgG anti- gliadin antibody levels. Expand
Predictive value for coeliac disease of antibodies to gliadin, endomysium, and jejunum in patients attending for jejunal biopsy.
TLDR
Detection of gliadin IgA by ELISA and to a lesser extent the endomysial IgA should allow better selection of patients for jejunal biopsy and thus make diagnosing coeliac disease simpler and more efficient. Expand
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TLDR
The results show that determination of EMA is more useful as a screening test for celiac disease and for follow-up than is AGA in children with Down syndrome, and confirms that Celiac disease is overrepresented among Swedish children with down syndrome. Expand
Celiac Disease: Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition
TLDR
Treatment of Celiac disease requires lifelong adherence to a diet that strictly eliminates products containing wheat, rye, and barley and complete recovery of the small intestinal damage can be expected with reversal of nutritional deficits and resolution of symptoms. Expand
The prevalence of celiac disease in at-risk groups of children in the United States.
TLDR
CD is not rare in the United States and may be as common as in Europe, and AGA and EMA are useful for identifying patients who should undergo a small intestinal biopsy. Expand
High prevalence of celiac disease in patients with type 1 diabetes detected by antibodies to endomysium and tissue transglutaminase.
TLDR
It is confirmed that CD is as prevalent in the pediatric type 1 diabetic population in British Columbia as it is in Europe and suggests that tTG serology may also be useful in monitoring response and compliance with a gluten-free diet. Expand
Coeliac disease in children and adolescents with IDDM: clinical characteristics and response to gluten‐free diet
TLDR
Serological screening for coeliac disease using the IgA endomysial test is effective, although the therapeutic benefit of dietary therapy in asymptomatic cases remains uncertain. Expand
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