Guided migration of neural stem cells derived from human embryonic stem cells by an electric field.

@article{Feng2012GuidedMO,
  title={Guided migration of neural stem cells derived from human embryonic stem cells by an electric field.},
  author={Jun-feng Feng and Jing Liu and Xiu-zhen Zhang and Lei Zhang and Ji-yao Jiang and Jan A Nolta and Min Zhao},
  journal={Stem cells},
  year={2012},
  volume={30 2},
  pages={
          349-55
        }
}
Small direct current (DC) electric fields (EFs) guide neurite growth and migration of rodent neural stem cells (NSCs). However, this could be species dependent. Therefore, it is critical to investigate how human NSCs (hNSCs) respond to EF before any possible clinical attempt. Aiming to characterize the EF-stimulated and guided migration of hNSCs, we derived hNSCs from a well-established human embryonic stem cell line H9. Small applied DC EFs, as low as 16 mV/mm, induced significant directional… CONTINUE READING