Guide wire-a sisted cannulation versus conventional contrast to prevent pancreatitis. A systematic review and meta-analysis based on randomized control trials.

Abstract

OBJECTIVE Through this systematic review and meta-analysis, we aim to clarify the differences between these two techniques, thus improving primary success cannulation and reducing complications during endoscopic retrograde cholangiopancreatography, primarily pancreatitis. METHODS A comprehensive search was conducted to search for data available up until June2015from the most important databases available in the health field: EMBASE, MEDLINE (via PubMed), Cochrane, LILACS and CENTRAL (via BVS), SCOPUS, the CAPES database (Brazil), and gray literature. RESULTS Nine randomized clinical trialsincluding2583 people were selected from20,198 studies for meta-analysis. Choledocholithiasis had been diagnosed in mostly (63.8%) of the patients, who were aged an average of 63.15 years. In those patients treated using the guide wire-assisted cannulation technique, provided a significantly lower instance of pancreatitis (RD=0.03; 95% CI: 0.01-0.05; I2= 45%) and greater primary success cannulation (RD=0.07; 95% CI: 0.03-0.12; I2=12%) than conventional contrast cannulation. CONCLUSIONS The guide wire-assisted technique, when compared to the conventional contrast technique, reduces the risk of pancreatitis and increases primary success cannulation rate. Thus, guide wire-assisted cannulation appears to be the most appropriate first-line cannulation technique.

Cite this paper

@article{Moura2016GuideWS, title={Guide wire-a sisted cannulation versus conventional contrast to prevent pancreatitis. A systematic review and meta-analysis based on randomized control trials.}, author={Eduardo Turiani Hourneaux de Moura and Eduardo Guimar{\~a}es Hourneaux de Moura and Wanderley Marques Bernardo and Spencer Cheng and Andr{\'e} Kondo and Diogo Turiani Hourneaux de Moura and Jos{\'e} Gonçalves Pereira Bravo and Everson Luiz de Almeida Artifon}, journal={Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru}, year={2016}, volume={36 4}, pages={308-319} }