Guggulsterone enhances glycosylated low density lipoprotein binding in rat liver

@article{Singh2007GuggulsteroneEG,
  title={Guggulsterone enhances glycosylated low density lipoprotein binding in rat liver},
  author={Vinita Singh and Narinder Kumar Kapoor},
  journal={Journal of Biosciences},
  year={2007},
  volume={17},
  pages={173-177}
}
Modification of low density lipoprotein by nonenzymic glycosylation resulted in decreased receptor-mediated lipoprotein catabolism. Guggulsterone treatment caused significant increase in binding of [125I] low density lipoprotein as well as [125I] glycosylated low density lipoprotein. Scatchard plot analysis of the binding activity revealed that under the influence of guggulsterone, the liver membrane contains increased amounts of a functional lipoprotein receptor that binds more low density… CONTINUE READING

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