Guarana Provides Additional Stimulation over Caffeine Alone in the Planarian Model

@article{Moustakas2015GuaranaPA,
  title={Guarana Provides Additional Stimulation over Caffeine Alone in the Planarian Model},
  author={Dimitrios Moustakas and Michael Mezzio and Branden R. Rodriguez and Mic Andre Constable and Mary E. Mulligan and Evelyn B. Voura},
  journal={PLoS ONE},
  year={2015},
  volume={10}
}
The stimulant effect of energy drinks is primarily attributed to the caffeine they contain. Many energy drinks also contain other ingredients that might enhance the tonic effects of these caffeinated beverages. One of these additives is guarana. Guarana is a climbing plant native to the Amazon whose seeds contain approximately four times the amount of caffeine found in coffee beans. The mix of other natural chemicals contained in guarana seeds is thought to heighten the stimulant effects of… 

Figures from this paper

Safety of Guarana Seed as a Dietary Ingredient: A Review.
TLDR
Overall, guarana is generally recognized as safe as a dietary ingredient marketed for its flavor and caffeine content if guidelines for caffeine intake are respected and consumption is not likely to be associated with any serious health risks when consumed properly.
A Comprehensive Study on Sports and Energy Drinks
Acute guarana poisoning: report of two cases.
TLDR
This report presents two cases of guarana overdose with the common caffeine poisoning symptoms and signs and treatment is symptomatic, mainly with benzodiazepines and by fluid and electrolyte substitution.
Behaviour-changing ingredients in soft drinks: an experiment developed by school children in partnership with a research scientist
Abstract A team of six children (13–14 years old) developed and conducted an experiment to assess the behaviour of the planarian flatworm, an invertebrate animal model, before, during and after
Effects of Paullinia cupana extract on lamotrigine pharmacokinetics in rats: A herb-drug interaction on the gastrointestinal tract with potential clinical impact.
Increased static postural sway after energy drink consumption: A randomized trial
TLDR
The results suggest that in healthy young adults, the sensory re-weighting mechanism can overcome postural perturbation and maintain overall postural control.
Some Popular Energy Shots and Their Ingredients: Are They Safe and Should They Be Used? A Literature Review
The current demanding and busy lifestyle has spawned the development of supplements that are marketed as energy and concentration boosters. Energy shots are one of the most popular such supplements
Arrhythmogenic effects of energy drinks
TLDR
2 cases of life‐threatening ventricular arrhythmias in young patients after consuming ED are reported and the ingredients of ED are reviewed, the physiologic effects on the cardiovascular system, and the available evidence suggesting arrh rhythmogenecity are reviewed.
A Systematic Review of the Effect of Dietary Supplements on Cognitive Performance in Healthy Young Adults and Military Personnel
TLDR
It is suggested that tyrosine or caffeine could be used in healthy young adults in a military context to enhance cognitive performance when personnel are sleep-deprived and preclude firm recommendations about the use of other specific dietary supplements.
Ankle complex musculature adaptations after Energy Drinks consumption in healthy young adult
TLDR
It appears that the additives found in Redbull and Bang produce an increased posterior sway, indicated by the faster activity observed on the anterior tibial muscle.
...
1
2
3
...

References

SHOWING 1-10 OF 71 REFERENCES
Behavioural effects of compounds co-consumed in dietary forms of caffeinated plants
TLDR
It is highlighted that more research aimed at understanding the effects of these compounds is needed and, more importantly, the synergistic relationship that they may have with caffeine.
The effects of caffeine, nicotine, ethanol, and tetrahydrocannabinol on exercise performance
TLDR
The aim of this brief review is to evaluate the effects of caffeine, nicotine, ethanol and THC by examining evidence supporting the ergogenic or ergolytic effects, and reviewing their impact as performance-altering aids used in recreational and elite sports.
Cognitive and physiological effects of an “energy drink”: an evaluation of the whole drink and of glucose, caffeine and herbal flavouring fractions
TLDR
There is some degree of synergy between the cognition-modulating effects of glucose and caffeine which merits further investigation, and the whole drink resulted in significantly improved performance on “secondary memory” and “speed of attention” factors.
Energy beverages: content and safety.
Exercise is making a resurgence in many countries, given its benefits for fitness as well as prevention of obesity. This trend has spawned many supplements that purport to aid performance, muscle
Major Components of Energy Drinks (Caffeine, Taurine, and Guarana) Exert Cytotoxic Effects on Human Neuronal SH-SY5Y Cells by Decreasing Reactive Oxygen Species Production
TLDR
Excessive removal of intracellular reactive oxygen species, to nonphysiological levels (or “antioxidative stress”), could be a cause of in vitro toxicity induced by these drugs.
Acute effects of guarana (Paullinia cupana Mart.) on mouse behaviour in forced swimming and open field tests
TLDR
Caffeine, but not guarana, could effectively block anAdenosine agonist, cyclopentyl adenosine (CPA)‐induced increase in swimming immobility suggesting that mechanism(s) other than the adenosinergic mechanism are involved in the antidepressant‐like activity of Guarana.
Guaraná's Journey from Regional Tonic to Aphrodisiac and Global Energy Drink
  • N. Smith, A. Atroch
  • Political Science
    Evidence-based complementary and alternative medicine : eCAM
  • 2010
TLDR
For some time, guaraná's high caffeine content was thought to be a detriment because of health concerns about excessive intake of caffeine-rich drinks, but it is precisely this quality, and the fact that it has a mysterious name and comes from an exotic land, that has propelled Guaraná into a global beverage.
...
1
2
3
4
5
...