Guanosine cyclic 3',5'-phosphate dependent protein kinase, a chimeric protein homologous with two separate protein families.

@article{Takio1984GuanosineC3,
  title={Guanosine cyclic 3',5'-phosphate dependent protein kinase, a chimeric protein homologous with two separate protein families.},
  author={Koji Takio and Roger D. Wade and Stephen Brent Smith and Edwin G. Krebs and K. A. Walsh and Koiti Titani},
  journal={Biochemistry},
  year={1984},
  volume={23 18},
  pages={4207-18}
}
The amino acid sequence of bovine lung cGMP-dependent protein kinase has been determined by degradation and alignment of two primary overlapping sets of peptides generated by cleavage at methionyl or arginyl residues. The protein contains 670 residues in a single N alpha-acetylated chain corresponding to a molecular weight of 76 331. The function of the molecule is considered in six segments of sequence which may correspond to four folding domains. From the amino terminus, the first segment is… CONTINUE READING
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