Guanosine 3':5'-monophosphate-dependent protein kinases in mammalian tissues.

  • Jer-Lai Kuo
  • Published 1974 in
    Proceedings of the National Academy of Sciences…

Abstract

The mammalian protein kinase activity stimulated preferentially by low concentrations of guanosine 3':5'-monophosphate (cyclic GMP), but not by adenosine 3':5'-monophosphate (cyclic AMP), was readily assayed in a modified incubation system that contained a neutral phosphate buffer, protein kinase modulator, and arginine-rich histone. Cyclic GMP-dependent… (More)

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