Growth stimulation and tumor promotion in skin.

@article{Frstenberger1983GrowthSA,
  title={Growth stimulation and tumor promotion in skin.},
  author={Gerhard F{\"u}rstenberger and Frederick W. Marks},
  journal={The Journal of investigative dermatology},
  year={1983},
  volume={81 1 Suppl},
  pages={
          157s-62s
        }
}
Stimulation of epidermal growth in adult mouse skin can be induced by chemical agents, such as phorbol esters and other skin mitogens, or by mechanical means, such as skin massage and skin wounding. It leads to different kinds of epidermal hyperproliferation, according to interference with mechanisms of endogenous growth control (G1 chalone) and to mediation by endogenous regulatory factors (prostaglandins). Certain phorbol esters and skin wounding induce epidermal hyperproliferation and, in… CONTINUE READING
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