Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae

@article{Yamochi1994GrowthSL,
  title={Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae},
  author={Wataru Yamochi and Kayoko Tanaka and Hideko Nonaka and Aya Maeda and Takashi Musha and Yoshimi Takai},
  journal={The Journal of Cell Biology},
  year={1994},
  volume={125},
  pages={1077 - 1093}
}
The Rho small GTP-binding protein family regulates various actomyosin-dependent cell functions, such as cell morphology, locomotion, cytokinesis, membrane ruffling, and smooth muscle contraction. In the yeast Saccharomyces cerevisiae, there is a homologue of mammalian RhoA, RHO1, which is essential for vegetative growth of yeast cells. To explore the function of the RHO1 gene, we isolated a recessive temperature-sensitive mutation of RHO1, rho1-104. The rho1-104 mutation caused amino acid… CONTINUE READING

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